Modified Release Technology

The mechanism of controlled release is achieved via a matrix or core-shell structure that offers obstacles to the drug's release. Controlled release of active ingredients is achieved through a matrix or core-shell structure in which the matrix or shell functions as an obstacle. A porosity, solubility, or erosion property of the matrix is used to slowly release the active ingredient through the outer coating at a defined rate.

Modified release j
Modified Release Technology

Controlled release particles are produced ranging from near and below 30μm to above one centimeter. Finally, the release rate can be changed to fit any desire: complete release may be slowed to a desired time to release into a desired location in the body, extended release might prolong the usage period, or extended release may be increased after a certain delay.

The release can also be governed by changes in pH, temperature, and solvents as well as matrix dissolution rate and porosity. To avoid gastric irritation, drugs are sometimes released enterically to wait in the small intestine. Immediate release and extended release may also be used to control the release of the product. Components and controlled release components may be combined at Raphe Pharma to produce the release rates you desire.